• 货号：GA133434
• CAS号：41443-28-1
• 分子式：C9H5N3O2
• 分子量：187.16
• Beilstein号：
• EC号：
• MDL号：
• PubChem编号：

属性
溶解性 Soluble in ethanol (1.2 mg/ml), DMSO (5 mg/ml), chloroform (10 mg/ml), acetonitrile (20 mg/ml), ethyl acetate, DMF (~30 mg/ml), and 1:1 solution of DMF:PBS(pH7.2) (~100 μg/ml). Insoluble in water.
描述
产品介绍 ODQ is a selective and potent GCS (soluble guanylyl cyclase, sGC) inhibitor that binds competitively with nitric oxide. The GCS (sGC) serves as a receptor for nitric oxide, which is involved in the production of cyclic guanosine monophosphate (cGMP). In prostate cancer cell studies, ODQ induced caspase-3, enhanced cell death, and blocked cell migration. Inhibition of GCS (sGC) through ODQ results in blocking the actions of nitric oxide on vascular and platelet smooth muscle.
别名 ODQ;ODQ
应用 A selective and potent sGC (soluble guanylyl cyclase) inhibitor.