别名
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2,3-双(2-甲氧基-4-硝基-5-磺苯基)-2H-四唑-5-甲酰胺内盐; 3,3‘-(1-(苯氨酰基)-3,4-四氮唑)-二(4-甲氧基-6-硝基)苯磺酸钠;;2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt; sodium 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2h-tetrazolium-5-carboxanilide inner salt; sodium 3,3‘-(1-(phenylamino)carbonyl)-3,4-tetrazolium-bis(4-methoxy-6-nitro)benzenesulfonic acid
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产品介绍
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XTT sodium salt is a tetrazolium sodium salt that can be used in the XTT assay for cell viablilty and cell proliferation. The reactions involving XTT sodium salt will result in the formation of a soluble formazan dye, an advantage over the use of MTT due to MTT requiring a solubilization step. another advantage of XTT sodium salt is higher sensitivity and greater dynamic range over MTT. XTT sodium salt has displayed applicability in monitoring biologcially active products with superoxide anion participation in DNA scission. The compound has also been used to asses valvular injury for testing cryopreserved cardiac valves.
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用途
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用于艾滋病和癌症测试。XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines.1 The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.
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