• 货号：GA138249
• CAS号：14663-23-1
• 分子式：C14H9N4NaO5
• 分子量：336.23
• Beilstein号：
• EC号：
• MDL号：
• PubChem编号：24278823

属性
描述
产品介绍 Dantrolene is a small molecule inhibitor of the Ryanodine receptor and a calcium channel protein inhibitor.Blockade of Ca2+ release from the sarcoendoplasmic reticulum, strongly related to excitation and contraction of muscles, generates a muscle relaxant effect correlated with Dantrolene. The neurotoxicity presented by pronounced glutamate activity is correlated to excessive rises in cytoplasmic Ca2+ levels, and Dantrolene is accordingly indicated as a neuroprotective agent against neurotrasmitter-induced excitotoxicity. Dantrolene, Sodium Salt is an inhibitor of RyR-1 and RyR-3.
别名 1-[[[5-(4-硝基苯)-2-呋喃基]亚甲基氨基]-2,4-咪唑啉二酮 钠盐;丹曲林钠;1-[[[5-(4-硝基苯)-2-呋喃亚甲基]氨基]-2,4-咪唑烷二酮钠盐;1-[(5--(p-Nitro-phenyl)-fur-furyl-idene)-amino]-hydan-toin sodium salt;1-[5-(-4-Nitrophenyl)furfurylideneamino]imidazolidine-2,4-dione sodium
生化机理 肌浆网 Ca2+ 释放的抑制剂；肌肉松弛剂。
应用 A calcium channel protein inhibitor.