• 货号：GA106466
• CAS号：60-56-0
• 分子式： C4H6N2S
• 分子量：114.17
• Beilstein号：
• EC号：
• MDL号：
• PubChem编号：

属性

密度 1.2800
熔点 145°C
沸点 280°C
溶解性 Soluble in DMSO (23 mg/ml at 25 °C), ethanol (23 mg/ml at 25 °C), chloroform (~222.22 mg/ml), water (~200 mg/ml), and methanol.
描述

产品介绍 A JAK/STAT signaling pathway inhibitor
别名 甲巯咪唑;1-甲基咪唑-2-硫醇;甲硫咪唑;1-Methyl-2-imidazolethiol; Methimazole; 1-Methylimidazole-2-thiol; Thiamazole; 2H-Imidazole-2-thione; 1,3-Dihydro-1-methyl-2H-imidazole-2-thione
生化机理 Methimazole is an antithyroid compound found to have antioxidant properties. Methimazole inhibits activation of the IFN-g-induced Janus kinase (JAK)/STAT signaling pathway in FRTL-5 thyroid cells, which may account for its immunodolulatory effects. Additionally, methimazole is an inhibitor of thyroperoxidase.
应用 用于甲亢原料药。