属性

敏感性 对空气敏感
密度 1.2680
熔点 106-109°C
描述

别名 4-氨基吲哚,4-吲哚胺;4-Indolamine,(Indol-4-yl)amine
应用 Reactant for preparation of:
? Inhibitors of bacterial thymidylate synthase
? Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)
? Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
? Protein kinase C θ (PKCθ) inhibitors
? Indolic non-peptidic HIV protease inhibitors
? Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
? Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors
? 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitors
? Short chain 4-substituted indoles as potent αvβ3 antagonist
? Ligands of serotonin transporter and 5-HT1A receptors