- GA115486
- 5192-23-4
- C8H8N2
- 132.16
-
属性
敏感性 对空气敏感
密度 1.2680
熔点 106-109°C
描述
别名 4-氨基吲哚,4-吲哚胺;4-Indolamine,(Indol-4-yl)amine
应用 Reactant for preparation of:
? Inhibitors of bacterial thymidylate synthase
? Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)
? Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
? Protein kinase C θ (PKCθ) inhibitors
? Indolic non-peptidic HIV protease inhibitors
? Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
? Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors
? 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitors
? Short chain 4-substituted indoles as potent αvβ3 antagonist
? Ligands of serotonin transporter and 5-HT1A receptors
信号词 Warning
风险声明 (欧洲) 36/37/38
安全声明(欧洲) 26,36
警示性声明 P261,P305+P351+P338
危害码(欧洲) Xi
危害声明 H315,H319,H335
个人防护设备 dust mask type N95 (US),Eyeshields,Gloves
WGK德国 3
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