别名
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N-羟基丁二酰亚胺;1-羟基-2,5-吡咯烷二酮;NHS;1-Hydroxy-2,5-pyrrolidinedione;HOSu;NHS
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产品介绍
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N-Hydroxysuccinimide, commonly known as NHS, is a hydroxylated succinimide that is widely used in the activation of carboxylic acids to NHS-esters to promote coupling with nucleophiles. This approach is most commonly employed in activating the free acid forms of fluorophores for promoting conjugation of these fluorophores to amine residues of proteins. Use of NHS ester activation has also been described in the synthesis of N-acyl amino acids.
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用途
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Useful in the carbodiimide method for improved amidations and peptide couplings.
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