• 货号：GA138447
• CAS号：20357-25-9
• 分子式：O2NC6H2-3,4-(OCH3)2CHO
• 分子量：211.17
• Beilstein号：
• EC号：243-762-1
• MDL号：
• PubChem编号：24856896

属性
描述
产品介绍 DMNB (4,5-dimethoxy-2-nitrobenzaldehyde) is a cell-permeable vanillin derivative and potent inhibitor of DNA-PK (IC50 = 15 μM). DMNB is shown in experiments to increase DR4/DR5 mRNA levels and their surface expression and decrease c-FLIP mRNA levels in K56. DMNB is also an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair.
别名 3,4-二甲氧基-6-硝基苯甲醛;;3,4-Dimethoxy-6-nitrobenzaldehyde;4,5-Dimethoxy-2-nitrobenzaldehyde