红霉素,98%使用说明书与操作注意事项

产品货号	重量	货期	优惠价
D13034-100g	100g	准现货	2692.00
D13034-25g	25g	准现货	891.00
D13034-5g	5g	准现货	350.00

产品货号

重量

货期

优惠价

数量

D13034-100g

100g

准现货

2692.00

D13034-25g

25g

准现货

891.00

D13034-5g

准现货

350.00

溶解性	熔于乙醇、甲醇、丙酮、氯仿、乙腈和乙酸乙酯，中等程度溶于醚、二氯甲烷和乙酸戊酯。难溶于水。微有引湿性，无臭，味苦。遇酸不稳定。水中溶解度:+/- 3 MG/ML。
熔点	138-140°C
密度	1.2000
旋光率	-74 ° (C=2, EtOH)
荧光	否
IC50	否
pK Values	否

溶解性

熔于乙醇、甲醇、丙酮、氯仿、乙腈和乙酸乙酯，中等程度溶于醚、二氯甲烷和乙酸戊酯。难溶于水。微有引湿性，无臭，味苦。遇酸不稳定。水中溶解度:+/- 3 MG/ML。

熔点

138-140°C

密度

1.2000

旋光率

-74 ° (C=2, EtOH)

荧光

否

IC50

否

pK Values

否

别名	红霉素 ;红霉素碱;(-)-Erythromycin ;Abomacetin
产品介绍	Erythromycin is a potent macrolide inhibitor of CYP3A4 with antiinflammatory and prokinetic properties. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Erythromycin is derived from Streptomyces erythreus and has been shown to inhibit NF-κB transcriptional activation, which leads to the inhibition of cytokine gene expression of IL-8 and lL-6. This mechanism was shown to occur via calcineruin-independent signaling T lymphocytes.
用途	A macrolide antibiotic protein synthesis inhibitor.Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.
生化机理	在转肽步骤抑制延长期，靠结合到核糖体上抑制细菌蛋白合成，对细菌诱发红霉素抗性。抗菌谱: 革兰氏阴性和阳性细菌。属大环内酯抗生素（Macrolide antibiotic）
备注	此产品所配溶液37°C只能保存3天，因此其储存溶液必须2-8°C保存.This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.

别名

红霉素 ;红霉素碱;(-)-Erythromycin ;Abomacetin

产品介绍

Erythromycin is a potent macrolide inhibitor of CYP3A4 with antiinflammatory and prokinetic properties. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Erythromycin is derived from Streptomyces erythreus and has been shown to inhibit NF-κB transcriptional activation, which leads to the inhibition of cytokine gene expression of IL-8 and lL-6. This mechanism was shown to occur via calcineruin-independent signaling T lymphocytes.

用途

A macrolide antibiotic protein synthesis inhibitor.Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.

生化机理

在转肽步骤抑制延长期，靠结合到核糖体上抑制细菌蛋白合成，对细菌诱发红霉素抗性。抗菌谱: 革兰氏阴性和阳性细菌。属大环内酯抗生素（Macrolide antibiotic）

备注

此产品所配溶液37°C只能保存3天，因此其储存溶液必须2-8°C保存.This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.

信号词	Warning
危害声明	H303
警示性声明	P312
个人防护设备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
危害码（欧洲）	Xn
风险声明 (欧洲)	R42/43
安全声明（欧洲）	S24;S37;S45
RIDADR	否
WGK德国	3
闪点（华氏）	N/A
Merck Index	3681
RTECS	KF437500
是否危化品	否

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