Soluble in chloroform (10 mg/ml), benzene, chlorobenzene, carbon disulfide, alkaline solutions, aqueous acid, ethanol (slightly), and ether (slightly). Insoluble in water.
敏感性
对光和热敏感
存贮条件
储存温度-20°C
折光率
1.72
沸点
925.16°C/760mmHg
熔点
192°C
密度
1.3740
荧光
否
IC50
否
pK Values
否
描述
别名
胆深红;胆红质;Hematoidin; Bilirubin IX-alpha; Hemetoidin; Principal bile pigment
产品介绍
Bilirubin is a principal pigment of bile and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. Serves as a physiological antioxidant. Reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This product corresponds to the unconjugated form. Extinction coefficient (454 nm, CHCl3):59,100-62,300 M-1cm-1.
用途
抗氧剂,保护膜磷脂免受过氧化氢自由基的氧化。即使在纳摩尔浓度也能保护神经元免受氧化损害。
生化机理
It appears to function as an antioxidant and efficient peroxyl radical scavenger, protecting membrane lipids from oxidation by these radicals. At nanomolar concentrations it has been shown to protect neurons from oxidative damage.
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