别名
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邻氯苯唑西林钠;3,3-二甲基-6-[5-甲基-3-(2-氯苯基)-4-异唑甲酰氨基]-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-甲酸钠盐;邻氯苯甲异噁唑青霉素钠;邻氯苯甲异恶唑青霉素钠;邻氯青霉素;Sodium cloxacillin; (2S,5R,6R)-6-[[[3-(2-Chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt
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产品介绍
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Cloxacillin Sodium是Cloxacillin的钠盐形式,是一种耐青霉素酶,耐酸,半合成的青霉素。
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用途
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A semi-synthetic antibiotic related to penicillin
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生化机理
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Cloxacillin is a semi-synthetic β-lactam antibiotic, related to penicillin, which suppresses the growth of gram-positive bacteria such as Staphylococcus by inhibiting the synthesis of peptidoglycan. Furthermore, cloxacillin inactivates the enzyme β-lactamase I, a side product produced by bacteria that are resistant to β-lactam antibiotics, by causing the acyl form of the enzyme to unfold. Escherichia coli containing plasmids carrying non-coding DsrA RNA are resistant to Cloxacilin. Cloxacillin sodium is an inhibitor of LACTB.
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