马来酸氯苯那敏 ,99%-elisa检测试剂盒-酶联免疫试剂盒-elisa kit供应商-上海晶抗生物工程有限公司

产品订购

看了又看以下产品

别名	马来酸氯苯那敏;扑尔敏;氯屈米通;马来那敏;Chlorphenamine maleate; Piriton;Puermin; Chlortrimeton
产品介绍	Chlorpheniramine Maleate是一种组胺H1受体拮抗剂，IC50为12 nM。
用途	An antagonist of the histamine H1-receptor.
生化机理	Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
备注	Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM.

标识符号	GHS06
信号词	Danger
危害声明	H301
警示性声明	P301 + P310
个人防护设备	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RIDADR	否
WGK德国	3
闪点（华氏）	N/A
RTECS	US6504000
是否危化品	否