Fenofibrate is a hypolipidemic compound which acts as a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 18 μM for mouse and EC50 = 30 μM for human). Fenofibrate also binds to PPARγ with at least 10-fold less affinity, and is inactive at PPARδ at concentrations up to 100 μM.
备注
Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative.
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