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别名
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四环素碱;Deschlorobiomycin; Ambramycin; Liquamycin;(2Z,4S,4aS,6S,12aS)-2-(Amino-hydroxymethylidene)-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione
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产品介绍
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Tetracycline is used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, Jurkat T lymphocyte cells and in cultured monocytes and macrophages.
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用途
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Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis.
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生化机理
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Tetracycline inhibits bacterial protein synthesis elongation at the level of aminoacyl-tRNA binding to the 30S ribosome. Tetracycline passively diffuses through porin channels in the bacterial cell membrane. It also binds to the bacterial 50S ribosomal subunit which may alter the cytoplasmic membrane, causing intracellular components to leak from bacterial cells. Mode of resistance is via loss of cell wall permeability.
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盐酸金霉素,USP级,900...
D-肉碱，98%
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利巴韦林，BR，98%
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色苷酸钠，BR，98%
维拉帕米盐酸盐，BR，99%
1-(4-叔丁基苯基)-3-...
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氯霉素，USP级，98%
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