玉米烯酮分析标准品,HPLC≥98%_ 17924-92-4_Zearalenone

标准品
中药标准品

玉米烯酮分析标准品,HPLC≥98%
货号：G63759 CAS号： 17924-92-4

英文名：Zearalenone

产品订购

产品货号	规格	货期	优惠价	数量
G63759-5mg	5mg	准现货	525.00

立即咨询说明书

看了又看以下产品

产品属性
产品信息
安全信息
产品评价

货号：G63759
CAS号：17924-92-4
分子式：C₁₈H₂₂O₅
分子量：318.36
Beilstein号： 1350216
EC号：200-835-2
MDL号： MFCD00133085
PubChem编号：24870569

属性

溶解性	Soluble in methanol (5 mg/ml), chloroform, ethanol (100 mM), and DMSO (100 mM). Insoluble in water
敏感性	对光线敏感
存贮条件	储存温度:-20℃
密度	1.1680
荧光	否
IC50	否
pK Values	否

描述

别名	玉米赤霉烯酮;F-2 toxin;[S-(E)]-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
产品介绍	Zearalenone, a phytoestrogenic mycotoxin usually produced by Fusarium species, is shown to be a cytotoxic compound, but alos binds to the estrogen receptor (ER) (IC50 values are 166 and 240 nM for ERβ and ERα respectively) and was found to stimulate the transcriptional activity of both subtypes at concentrations between 1 - 10 nM. This agent has demonstrated the ability to induce apoptosis via activation of mitochondrial release of Cytochrome c, production of reactive oxygen species (ROS), activation of caspase-3 and caspase-8, and induction of endoplasmic reticulum stress. Additional studies suggest that Zearalenone also up-regulates Bax expression and down-regulates Bcl-xL expression in cells, which also contribute to a halt in cell proliferation. The cell growth arrests caused by this mycotoxin seem to take place during the G1 phase of the cell cycle.
用途	A phytoestrogenic mycotoxin and ER activator
生化机理	Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans

99%- 好评度 -
共有(72)人参考评价

很好

99%

较好

0%

一般

0%
我要评论
仅对购买过该产品的用户开放！

全部(0)
很好(0)
较好(0)
一般(0)

{uname}

{comment_time|今天}

{content|默认评论}

{uname}

{comment_time|今天}

{content|默认好评}

{uname}

{comment_time|今天}

{content|默认中评}

{uname}

{comment_time|今天}

{content|默认差评}

相似产品

返回顶部 微信咨询

021-54720761 021-54720761 点我QQ咨询点我QQ咨询