相关栏目：
  1. 细胞库
  2. 永生化细胞
  • HPMEC人肺微血管内皮细胞永生化

  • HPMEC

产品货号货期 优惠价 数量
JLC_K6130 3-7天 询价
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  • 产品信息

Cell Specification
The pulmonary microvascular endothelial cells (PMEC) lining the pulmonary vasculature form a semiselective barrier which is critical for gas exchange and the regulation of fluid, macromolecules, and
cells between the blood and the interstitial compartments in the lung [1]. PMEC also produce
angiotensin-converting enzyme to activate angiotensin, a peptide hormone which causes
vasoconstriction and increases blood pressure [2]. PMEC further plays an important role in modulating
cellular properties of pulmonary mesenchymal cells and inflammatory events [3, 4]. Such functions of
PMEC are implicated in acute lung injury, pulmonary hypertension, edema, embolism, and lung cancer
development.
HPMEC from ScienCell Research Laboratories are isolated from human lung. HPMEC are
cryopreserved at passage one and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume.
HPMEC are characterized by immunofluorescence with antibodies specific to vWF/Factor VIII and
CD31 (PECAM). HPMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and
fungi. HPMEC are guaranteed to further expand for 10 population doublings under the conditions
provided by ScienCell Research Laboratories.

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