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产品介绍
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Azelaic acid is a dicarboxylic acid that exhibits anti-inflammatory activity. It is known for it’s anti acne activity in vitro. Azelaic acid directly inhibits kallikrein 5 (KLK5), downregulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and upregulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPARν is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes. This compound displays antiacne and anticancer potential as well, inhibiting the proliferation of cutaneous melanoma due to suppression of mitochondrial oxidoreductive activity and DNA synthesis.
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(-)-乳酸乙酯 98%
缩水甘油 ,96%
苯磺酰氯 ,96%
苯基二氯膦 ,98%
苯甲腈 ,>99% (GC)
苯甲醛 ,AR,≥98%(G...
苯胺 ,ACS, ≥99.0...
DL-苦杏仁酸 AR,99...
山俞酸(二十二酸) tec...
对氨基苯磺酸 ,GR,99....
5-氯-2-硝基苯甲酸 ,9...
三乙胺盐酸盐(盐酸三乙胺)，...
2-甲氧基苯甲醛，3% 
4-羟基苯乙酮,99.5%
丙酮酸钠，99%
硬脂酸镁，USP
丁二酸，99.7%
丁二酸钠，99%
3-碘苯甲酸，98%
月桂酸，99%
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